Nutritional Soup for
Cancer
An enormous
amount of scientific literature
shows beyond a reasonable doubt that
many components of fruits,
vegetables, herbs and mushrooms have
the ability to retard and treat
cancer—at least in animals and test
tubes.1-5 Similar results in human
studies, on the other hand, are few
and far between, primarily because
human studies have yet to be
performed. One exception was the
fish-oil study reported in the
January 1998 issue of Cancer, in
which a large, well-designed,
double-blind study showed fish oil
more than doubled the survival time
of patients with advanced cancers of
the breast, colon, lung and
pancreas.6 Tragically, these
encouraging results did not catch
the interest of the medical
profession, the media or the public.
Nor did the big cancer organizations
and institutions put their prestige
or money on the line in order to
replicate the study. Perhaps their
interest will perk up with news of a
nutritional broth that may have
tripled the survival time of
patients with advanced non-small
cell lung cancer.
Non-small
cell lung cancer kills more than
400,000 Americans each year. Knowing
conventional therapies are only
marginally effective in treating
this condition,7 researchers at the
Connecticut Institute for Aging and
Cancer in Milford along with those
at the Czech Republic's University
of Palacky tested an experimental
nutritional treatment on six
patients with advanced (Stage III or
Stage IV) non-small cell lung cancer
compared to 13 comparable lung
cancer victims who did not receive
the treatment. The design, however,
was not double-blind, meaning both
patients and doctors knew who had
received the therapy and who had
not. Regardless of which group
patients were in, each continued
their standard chemotherapy
treatments.
The
researchers' experimental cancer
treatment was nothing more or less
than 30 g a day of soup stock
prepared from a broad array of
herbs, vegetables and mushrooms,
including soybeans, shiitake
mushrooms (Lentinus edodes), mung
beans, red dates, scallions, garlic
(Allium sativum), lentils, leeks,
hawthorn fruit (Crataegus
pinnatifida), onions, ginseng (Panax
spp.), angelica root (Angelica spp.),
licorice (Glycyrrhiza spp.),
dandelion root (Taraxacum officinale),
senegal root (Polygala senega),
ginger (Zingiber officinalis),
olives, sesame seeds and parsley.
The complex is now a commercially
available product produced in
Milford, Conn.
Although
vegetable soup chemotherapy may
sound silly, a 24-month follow-up
revealed remarkable results. For
example, control patients lost an
average of 11.6 percent of their
body weight, while those taking the
vegetable soup lost only 2.1
percent. Moreover, vegetable soup
patients scored much higher on their
day-to-day quality of life function
tests as measured by the standard
Karnofsky Performance Scale (KPS).
Among control subjects, KPS scores
fell from a respectable 78 at the
start to a struggling 55 within
three months, while the vegetable
soup patients' average score
actually improved from 75 at the
start to a follow-up value of 80.
The most
impressive result of this study,
however, was the apparent survival
advantage of those taking the
experimental broth. Excluding three
patients who died early, the median
survival among the remaining 10
control patients was 4.5 months,
with a 95 percent confidence range
of four to seven months. In
contrast, half the soup patients
were still alive at 15.5 months,
with a 95 percent confidence range
of nine to 18 months. Thus, the
broth treatment more than tripled
the median survival rate, far
surpassing the power of any
conventional therapy.
Of course,
these wonderful results could be a
fluke. Larger, double-blind and
better-controlled studies may show
that vegetable soup is not, in fact,
effective as a cancer treatment. But
considering there is a chance that
it may be, the question is whether
such pivotal research will actually
be performed.
Preliminary
signs do offer a smidgen of hope, as
the research report itself
acknowledges several internationally
respected leaders of the orthodox
cancer elite. Perhaps one or more of
these "union" leaders will place
their personal prestige on the line
in order to vouch for continued
research into the role herbs, fruits
and vegetables play in cancer
prevention and cure. If so, a large
double-blind study could start
promptly, and, given the deadly
nature of lung cancer, the results
would follow quickly. The interests
of both patients and scientists
would be served by determining if a
bowl of mere vegetable soup has the
power to double as a chemotherapy
treatment.
Richard N.
Podell, M.D., M.P.H., is director of
the Podell Medical Center in New
Providence, N.J.
References
1. Hartwell
JL. Plants used against cancer: a
survey. (Lloydia; 1971. p
30:379-416; 31:71-170, 32: 70-107,
153-205, 247-96—1969. 33:97-194,
288-92—1970. 34:103-60, 204-55,
301-60, 368-438—1971.
2. Evans SM,
et al. Protection against metastasis
of radiation-induced thymic
lymphosarcoma and weight loss in
C57BL/6NCrlBR mice by an autoclave
resistant factor present in
soybeans. Radiat Res
1992;132:259-62.
3. Peterson
G. Genistein and biochanin A inhibit
the growth of human prostate cancer
cells not epidermal growth factor
receptor tyrosine
autophosphorylation. Prostate
1993;22:335-45.
4.Shamsuddkin AM, Ullah A.
Suppression of large intestinal
cancer in F344 rats by inositol
hexaphosphate. Carcinogenesis
1988;9:577-80.
5. Chihara
G, et al. Antitumor and
metastasis-inhibitory activities of
lentinan as an immunomodulator: an
overview. Cancer Detect Prev Suppl
1987;1:423-43.
6. Gogos C,
et. al. Dietary Omega-3
polyunsaturated fatty acids plus
vitamin E restore immunodeficiency
and prolong survival for severely
ill patients with generalized
malignancy: a randomized control
trial. Cancer 1998;82:395-402.
7. Sun AS,
et al. Phase I/II study of stage II
and IV non-small cell lung cancer
patients taking a specific dietary
supplement. Nutr Cancer
1999;34(1):62-9.
Tough on crime, to hell with the
causes of crime if they make money
Research shows a direct link between
junk food and violent behaviour. But
governments are in cahoots with the
industry
George Monbiot
Tuesday May 2, 2006
The Guardian
Does television cause crime? The
idea that people copy the
violence they watch is debated
endlessly by criminologists. But
this column concerns an odder
and perhaps more interesting
idea: if crime leaps out of the
box, it is not the programmes
that are responsible as much as
the material in between. It
proposes that violence emerges
from those blissful images of
family life, purged of all
darkness, that we see in the
advertisements.
Let me begin, in constructing
this strange argument, with a
paper published in the latest
edition of Archives of
Pediatrics and Adolescent
Medicine. It provides empirical
support for the contention that
children who watch more
television eat more of the foods
it advertises. "Each hour
increase in television viewing,"
it found, "was associated with
an additional 167 kilocalories
per day." Most of these extra
calories were contained in junk
foods: fizzy drinks, crisps,
biscuits, sweets, burgers and
chicken nuggets. Watching
television, the paper reported,
"is also inversely associated
with intake of fruit and
vegetables".
There is no longer any
serious debate about what a TV
diet does to your body. A
government survey published last
month shows that the proportion
of children in English secondary
schools who are clinically obese
has almost doubled in 10 years.
Today, 27% of girls and 24% of
boys between 11 and 15 years old
suffer from this condition,
which means they are far more
likely to contract diabetes and
to die before the age of 50. But
the more interesting question is
what this diet might do to your
mind. There are now scores of
studies suggesting that it hurts
the brain as much as it hurts
the heart and the pancreas.
Among the many proposed
associations is a link between
bad food and violent or
antisocial behaviour.
The most spectacular results
were those reported in the
Journal of Nutritional and
Environmental Medicine in 1997.
The researchers had conducted a
double-blind, controlled
experiment in a jail for chronic
offenders aged between 13 and
17. Many of the boys there were
deficient in certain nutrients.
They consumed, on average, only
63% of the iron, 42% of the
magnesium, 39% of the zinc, 39%
of the vitamin B12 and 34% of
the folate in the US
government's recommended daily
allowance. The researchers
treated half the inmates with
capsules containing the missing
nutrients, and half with
placebos. They also counselled
all the prisoners in the trial
about improving their diets. The
number of violent incidents
caused by inmates in the control
group (those taking the
placebos) fell by 56%, and in
the experimental group by 80%.
But among the inmates in the
placebo group who refused to
improve their diets, there was
no reduction. The researchers
also wired their subjects to an
electroencephalograph to record
brainwave patterns, and found a
major decrease in abnormalities
after 13 weeks on supplements.
A similar paper, published in
2002 in the British Journal of
Psychiatry, found that among
young adult prisoners given
supplements of the vitamins,
minerals and fatty acids in
which they were deficient,
disciplinary offences fell by
26% in the experimental group,
and not at all in the control
group. Researchers in Finland
found that all 68 of the violent
offenders they tested during
another study suffered from
reactive hypoglycaemia: an
abnormal tolerance of glucose
caused by an excessive
consumption of sugar,
carbohydrates and stimulants
such as caffeine.
In March this year the lead
author of the 2002 report,
Bernard Gesch, told the
Ecologist magazine that "having
a bad diet is now a better
predictor of future violence
than past violent behaviour ...
Likewise, a diagnosis of
psychopathy, generally perceived
as being a better predictor than
a criminal past, is still miles
behind what you can predict just
from looking at what a person
eats."
Why should a link between
diet and behaviour be
surprising? Quite aside from the
physiological effects of eating
too much sugar (apparent to
anyone who has attended a
children's party), the brain,
whose function depends on
precise biochemical processes,
can't work properly with
insufficient raw materials. The
most important of these appear
to be unsaturated fatty acids
(especially the omega 3 types),
zinc, magnesium, iron, folate
and the B vitamins, which happen
to be those in which the
prisoners in the 1997 study were
most deficient.
A report published at the end
of last year by the pressure
group Sustain explained what
appear to be clear links between
deteriorating diets and the
growth of depression,
behavioural problems,
Alzheimer's and other forms of
mental illness. Sixty per cent
of the dry weight of the brain
is fat, which is "unique in the
body for being predominantly
composed of highly unsaturated
fatty acids". Zinc and magnesium
affect both its metabolism of
lipids and its production of
neurotransmitters - the
chemicals which permit the nerve
cells to communicate with each
other.
The more junk you eat, the
less room you have for foods
which contain the chemicals the
brain needs. This is not to
suggest that food advertisers
are solely responsible for the
decline in the nutrients we
consume. As Graham Harvey's new
book We Want Real Food shows,
industrial farming, dependent on
artificial fertilisers, has
greatly reduced the mineral
content of vegetables, while the
quality of meat and milk has
also declined. Nor do these
findings suggest that a poor
diet is the sole cause of crime
and antisocial behaviour. But
the studies I have read suggest
that any government that claims
to take crime seriously should
start hitting the advertisers.
Instead, our government sits
back while the television
regulator, Ofcom, canoodles with
the food industry. While drawing
up its plans to control junk
food adverts, Ofcom held 29
meetings with food producers and
advertisers and just four with
health and consumer groups. The
results can be seen in the
consultation document it
published. It proposes to do
nothing about adverts among
programmes made for children
over nine and nothing about the
adverts the younger children
watch most often. Which? reports
that the most popular ITV
programmes among two- to
nine-year-olds are Dancing on
Ice, Coronation Street and
Emmerdale, but Ofcom plans to
regulate only the programmes
made specifically for the
under-nines. It claims that
tougher rules would cost the
industry too much. To sustain
the share values of the
commercial broadcasters, Ofcom
is prepared to sacrifice the
physical and psychological
wellbeing of our children.
At the European level, the
collusion is even more obvious.
Last week, Viviane Reding, the
European media commissioner,
spoke to a group of broadcasters
about her plans to allow product
placement in European TV
programmes (this means that the
advertisers would be allowed to
promote their wares during,
rather than just between, the
programmes). She complained that
her proposal had been attacked
by the European parliament. "You
have to fight if you want to
keep it," she told the TV
executives. "I would like to
make it very clear that I need
your support in this."
I spent much of last week
trying to discover whether the
Home Office is taking the
research into the links between
diet and crime seriously. In the
past, it has insisted that
further studies are needed,
while failing to fund them.
First my request was met with
incredulity, then I was
stonewalled. Tough on crime. To
hell with the causes of crime.
www.monbiot.com
Journals 'regularly publish
fraudulent research'
David Batty
Wednesday May 3, 2006
Fraudulent research regularly
appears in the 30,000 scientific
journals published worldwide, a
former editor of the British Medical
Journal (BMJ) said today.
Even when journals discover that
published research is fabricated or
falsified they rarely retract the
findings, according to Richard
Smith, who was also chief executive
of the BMJ publishing group.
When journals decide not to
publish studies because they suspect
misconduct, they often fail to alert
the researchers' employers or
medical authorities, such as the
Department of Health and the General
Medical Council, he added.
Writing in the latest edition of the
Journal of the Royal Society of
Medicine, Dr Smith called on editors
to blow the whistle on bad research
and to use their clout to pressure
universities into taking action
against dodgy researchers.
"In many ways editors are
privileged 'whistleblowers' with the
power to publish and expose
institutions who fail to investigate
alleged research misconduct," he
said.
But the former BMJ editor said it
was likely that research fraud was
"equally common" in the 30,000 plus
scientific journals across the globe
but was "invariably covered up".
His call for action comes in the
wake of several high profile cases
of fraudulent research, including
the Korean scientist Hwang Woo-suk
who fabricated stem cell research
that it was claimed would open up
new ways to treat diseases like
Parkinson's.
Dr Smith criticised the failure
of scientific institutions,
including universities, to
discipline dodgy researchers even
when alerted to problems by
journals.
"Few countries have measures in
place to ensure research is carried
out ethically," he said.
"Most cases are not publicised.
They are simply not recognised,
covered up altogether or the guilty
researcher is urged to retrain, move
to another institution or retire
from research."
Dr Smith called for the UK
Research Integrity Office, launched
last month to develop a code of
practice for researchers, to be
given stronger powers to investigate
allegation of fraudulent or
unethical work.
The Committee on Publication
Ethics, which advises scientific
journals, estimates that there are
about 50 cases of seriously
fraudulent research in major
institutions in Britain a year.
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September 30th, 2004 8:43 pm
Health-care firms on
lookout for Michael Moore
By Bruce
Japsen /
Chicago Tribune
The latest buzz in the health-care industry has
nothing to do with new drugs or medical treatments.
It's all about moviemaker Michael Moore and where
he's lurking these days.
Some of the nation's biggest drug manufacturers
and health insurance plans confirm they have issued
warnings to their sales representatives and other
employees in recent weeks, telling them to be on the
lookout for the shaggy filmmaker in his trademark
baseball cap. And, under no circumstances, are they
to talk to Moore.
The industry's red alert was prompted by word
that Moore plans to aim his camera lens at the
health-care industry, much as he did with other
targets, most recently President Bush in "Fahrenheit
9/11."
The $100 million box office documentary-style
film presented Bush's war on terror as ill-advised
and corrupt, angering the president's supporters
while drawing cheers from Bush foes.
The planned movie, tentatively titled "Sicko," is
expected to focus on health-care industry business
practices, specifically those of the managed-care
and pharmaceutical industries, which have both been
mentioned in Moore's recent speeches and interviews,
his spokesman said.
Health-care companies are hardly enthused.
"What our society really needs is a serious
debate about overall health care based on facts, not
just another one-sided micro-mockumentary," said
Court Rosen, spokesman with the drug industry's
Washington lobby, Pharmaceutical Research and
Manufacturers of America.
But Moore's people seemed amused by the
industry's call to arms, saying health-care
companies obviously have reason to be concerned if
they feel the need to put their employees on guard.
Moore representatives say there isn't even a
timetable for production to begin, and financing has
yet to be finalized.
"Everything he does is well-documented, so I can
understand why they would be so worried," said Moore
spokesman Mark Benoit.
Industry observers don't think it will be
difficult for Moore to find real-life examples,
since the business practices of HMOs and certain
other health plan business practices that encourage
low-cost medical care have long been criticized as
short-changing patients.
Practices targeted
Meanwhile, drug industry marketing practices have
been a target of prosecutors and lawmakers who say
they can lead to unnecessary prescriptions by
doctors or to higher health-care costs.
The industry's gift-giving practices, intended to
win physician loyalty to certain drugs, have been of
particular concern in a climate of growing consumer
outrage over drug costs, which have risen at an
annual rate of 15 percent during each of the last
four years, far exceeding inflation.
"We would welcome any public disclosure on the
way this multibillion-dollar industry works," said
Lynda DeLaforgue, co-director of consumer group
Citizen Action Illinois. "They would certainly have
reason to be concerned about any group looking into
their business practices, looking into the amount of
money that they use to influence the political and
legislative process. These are obviously the typical
things Mr. Moore delves into deeper."
If industry reports on Moore sightings are to be
believed, the filmmaker himself is taking a page out
of drugmakers' handbooks to do his movie by offering
medical professionals payments for access to their
offices.
Companies have warned their sales representatives
to be on the lookout for camera phones and reports
of Moore representatives offering $50,000 to
doctors' offices to place hidden cameras or $5,000
to sales representatives willing to be filmed,
according to a representative of one drugmaker, who
asked not to be identified.
Moore's spokesman would not comment on any
production activity or allegations of payments to
drug company employees.
Miramax, which has been mentioned in published
reports as financing and distributing Moore's film
on the health-care industry, said a deal is in the
works but it has "yet to be finalized," a Miramax
spokesman said. Miramax would not comment on Moore's
plans for the film, and Moore was unavailable for
comment.
In the Chicago area, the Moore film has been a
topic of discussion in the public relations and
marketing departments at both Abbott Laboratories of
North Chicago and TAP Pharmaceutical Products Inc.
of Lake Forest.
"We have communicated a reminder of our media
policy," said Abbott spokeswoman Laureen Cassidy.
"If Abbott representatives are directly
approached by media, we have provided them with some
helpful reminders for interacting with the media,"
she added. "This information is shared at routine
training meetings held throughout the year. We also
share this information when individuals are staffing
an Abbott booth at medical meetings."
Education on ethics
Even before it was reported that Moore was
thinking about a movie on the health-care industry,
Abbott and TAP took exhaustive measures to educate
their sales forces on ethical business practices.
In 2001, TAP--a joint venture of Abbott and
Takeda Pharmaceutical Co. of Japan--pleaded guilty
to a charge of conspiring with doctors in the
mid-1990s to bill government insurers for free
samples of the prostate cancer drug Lupron and paid
an industry record $885 million to settle
allegations of wrongdoing.
In July, 11 current and former TAP sales
representatives not covered by the 2001 settlement
were either acquitted or had charges against them
dismissed. The trial in federal court in Boston
involved charges of illegal marketing practices.
Neither TAP nor Abbott would comment on the Moore
movie. They said they do not believe they are a
focus of it.
A pharmaceutical professionals' Web site,
Cafepharma, has been abuzz in recent weeks about
Moore sightings and rumors the famed film producer
is trying to recruit pharmaceutical sales
representatives for his documentary.
Health plans, too, say they are aware of the film
but are not going to let it distract them from
providing patient care for their subscribers.
"Michael Moore is a major Hollywood entertainer
and while we have heard through the Hollywood press
that he has signed a deal for his next movie, our
industry is much more focused on the needs of the
American people advancing a positive policy agenda
in Washington and across the country to make
high-quality health care affordable for millions of
Americans," said Mohit Ghose, spokesman for
America's Health Insurance Plans.
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